If you are using the Windows or Linux 64-bit version of Bio7 and often a freezing of the application occurs this could be related to a PermGen space error which occurs if the PermGen space of the running JVM of Bio7 is to low. The consequence is a Java.lang.OutOfMemoryError: PermGen space and the application is not responsive anymore. The solution is to increase the PermGen space in the Bio7.ini file (in the Bio7 installation folder beside the Bio7.exe or Bio7 start file).
Simply add or increase the following argument to the Bio7.ini file:
-XX:MaxPermSize=256m (Default since Bio7 1.6!)
which increases the space if needed.